This report presents the results of a project on analysis of human vulnerability and adaptation to climate change in the Amboro Madidi Corridor, Bolivia (AMC) implemented by the Grupo Nacional de Trabajo para la Participacion (GNTP) with technical and financial support from Conservation International. The central objective of this project was to contribute to conservation of globally significant biodiversity in the Tropical Andes Hotspot and AMC, and to support development of policy/intervention responses that enhance human well being and adaptive capacity across this landscape. This project will contribute increasing understanding of the linkages between climate change and human well being. In particular this research provides evidence of how human well being is, and will be, affected by climate change at different altitudes in a landscape which is a global priority for biodiversity conservation. While the impacts of climate change vary globally, lessons from this study can still potentially inform the efforts in other regions, particularly in its innovative approach to integrating information gained from scientific modeling of climate change projections, vulnerability assessment and mapping, and participatory community based adaption assessments. In our review of the existing literature, we found few studies that combined these qualities and data.